CISH is induced during DC development and regulates DC-mediated CTL activation
نویسندگان
چکیده
منابع مشابه
Regulation of DC development and DC-mediated T-cell immunity via CISH
Cytokine inducible SH2-containing protein (CISH) plays a crucial role in type 1 dendritic cell (DC) development as well as in the DC-mediated activation of cytotoxic T lymphocytes (CTLs). CISH expression at late DC developmental stages shuts down the proliferation of DC progenitors by negatively regulating signal transducer and activator of transcription 5 (STAT5) and facilitates the differenti...
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ژورنال
عنوان ژورنال: European Journal of Immunology
سال: 2011
ISSN: 0014-2980
DOI: 10.1002/eji.201141846